Summary tables for Linking somatic mutations in cancer to the electronic properties of DNA
Abstract
This dataset accompanies the paper: > Linking somatic mutations in cancer to the electronic properties of DNA Code to reproduce all figures and analyses is available at: https://github.com/3BioCompBio/MutationvIP --- Overview The paper investigates whether the electronic properties of DNA — quantified by the vertical Ionization Potential (vIP) score, a quantum-chemistry-derived measure of the ionization energy of each nucleotide k-mer — predict where somatic mutations preferentially accumulate in the human genome. A lower vIP indicates a more electron-rich (more oxidizable) context; we show that high-vIP contexts systematically accumulate fewer mutations across a broad range of mutation types and databases. All genomic coordinates use the GRCh38/hg38 assembly.
Fields of Study & Subjects
Cancer Genomics and Diagnostics
Fractal and DNA sequence analysis
DNA and Nucleic Acid Chemistry
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 10 March 2026
- Language
- EN
- Document type
- Dataset