SYNTHESIS OF 10-DECYL-3-(2'-HYDROXYMETHYL) BENZO[g] PTERIDINE -2, 4-DIONE PHOSPHATE AND ITS INCORPORATION IN CATIONIC VESICLES

Synthetic flavin molecules are important biomolecules which when incorporated into lipid bilayers by designing them as amphiphilic compounds with both a hydrophilic flavin head and a hydrophobic tail, can act as catalysts for electron transport across the membrane, mimicking processes seen in cellular respiration and photosynthesis. In the present work a new anionic flavin was synthesized and incorporated in cationic (DDAB) vesicles. The electron micrograph and UV-visible spectra show that amphiphilic isoalloxazine is located in more polar inner water bilayer interface of the vesicles.