AN APPROACH TO ETIOPATHOLOGICAL DIAGNOSTIC STUDY ON KOSHTASHAKHASHRITA KAMALA OF RAKTAVAHA SROTODUSHTI THROUGH LIVER FUNCTION TEST

Ayurveda emphasizes the pivotal role of Srotas as fundamental channels responsible for the maintenance of normal physiology and the manifestation of disease. Kamala, a Pittaja Nanatmaja Vyadhi classified under Raktapradoshaja Vyadhi, exemplifies Srotodushti, particularly involving Raktavaha Srotas. Based on Samprapti, Kamala is categorized into Koshtashakhashrita Kamala and Shakhashrita Kamala, with the former being predominantly associated with Pitta aggravation. Aim and Objectives: The present study aimed to evaluate liver function test (LFT) changes in Koshtashakhashrita Kamala. The objectives were: (1) to study the etiopathogenesis of Koshtashakhashrita Kamala, (2) to diagnose the condition through Roga-Rogi Pariksha, and (3) to assess biochemical alterations in liver function parameters. Methodology: A clinical observational study was conducted on 60 patients diagnosed with Koshtashakhashrita Kamala, selected randomly irrespective of age, sex, religion, occupation, and socio-economic status. A specially designed proforma was used for detailed history taking and clinical examination based on classical Ayurvedic signs and symptoms. Liver function tests, including serum bilirubin, SGPT, and SGOT, were evaluated. Results: The study revealed a significant elevation of total bilirubin, predominantly the direct fraction, indicating hepatocellular dysfunction. Mild to moderate increases in SGPT and SGOT levels were also observed, suggesting primary involvement of the Yakrit, the Mula of Raktavaha Srotas. These findings correlate with Ranjaka and Pachaka Pitta Dushti. Conclusion: Altered liver function parameters substantiate Raktavaha Srotomula Dushti as a key pathological factor in Koshtashakhashrita Kamala and provide a reliable diagnostic and prognostic basis for planning effective Chikitsa aimed at Samprapti Vighatana.