"A SINGLE ARM CLINICAL TRIAL TO EVALUATE THE EFFICACY OF BRAHMIGHRITA IN PREMENSTRUAL SYNDROME"

Premenstrual Syndrome (PMS) is a psychoneuroendocrine disorder marked by cyclic emotional, behavioural and physical symptoms during the luteal phase, resolving with menstruation. It affects many women of reproductive age due to hormonal fluctuations, altered serotonin and GABA activity and individual sensitivity. Common symptoms include irritability, mood swings, anxiety, breast tenderness, bloating and fatigue. PMS is not mentioned in Ayurveda directly but can be correlated with Pitta Prakopa with Vata Sanchya Awastha is Rituvyateeta kala symptomatically. Brahmighrita with its Medhya and Rasayana properties promotes mental calmness and emotional stability. Ingredients like Trikatu, Danti, Aragwadha and Vidanga alleviate somatic symptoms through Doshaghna action offering holistic relief. Bacosides in Brahmi modulate serotonergic and dopaminergic pathways. Overall Brahmighrita exhibits Tridoshaghna, Vedanasthapana, Balya and Medhya properties, making it beneficial in PMS management.