ANTIOXIDANT-DRIVEN HEPATOPROTECTION: INVESTIGATING COFFEA BENGHALENSIS AND XYLOSMA LONGIFOLIA IN CHEMICALLY INDUCED LIVER DAMAGE

Hepatotoxicity refers to liver dysfunction or liver damage associated with exposure to an excess of drugs or other xenobiotics.[1] Chemicals that cause liver injury are known as hepatotoxins or hepatotoxicants. Hepatotoxicants are exogenous compounds of clinical relevance and include overdoses of certain medicinal drugs, industrial chemicals, natural toxins such as microcystins, herbal remedies, and dietary supplements.[2,3] Importantly, some drugs may cause liver injury even when administered within therapeutic dose ranges.