EFFICACY OF YASHTIMADHU (GLYCYRRHIZA GLABRA LINN.) AS SINGLE DRUG THERAPY IN THE MANAGEMENT OF AMLAPITTA- A CLINICAL STUDY

Amlapitta, a common gastrointestinal disorder described in Ayurveda, is characterized by symptoms such as acid regurgitation, heartburn, nausea, indigestion, and epigastric discomfort. It is primarily caused by Agnimandya and vitiation of Pitta doṣa. Modern correlation aligns Amlapitta with hyperacidity and gastroesophageal reflux related conditions. Yashtimadhu (Glycyrrhiza glabra Linn.), known for its Madhura rasa, Sheeta virya, Pitta shamaka, Vraṇa-Ropaka, and Shothahara properties, has been traditionally advocated in the management of acid peptic disorders. Ekala Dravya Chikitsa is a fundamental therapeutic principle of Ayurveda, emphasizing the use of a single appropriately selected drug. Amlapitta is a common gastrointestinal disorder caused by Pitta aggravation. The present study is to evaluate the efficacy of Yashtimadhu (Glycyrrhiza glabra Linn.) as a single drug therapy in the management of Amlapitta. The methods used in the present study is An open label, single arm clinical study was conducted in a patient diagnosed with Amlapitta. Yashtimadhu Churna (3 gms twice daily with milk) was administered for 21 days. Clinical symptoms were assessed before and after treatment. Significant improvement was observed in heartburn, sour belching, nausea, indigestion, and epigastric discomfort without any adverse effects. Therefore the Yashtimadhu as a single drug therapy was effective and safe in the management of Amlapitta, supporting the clinical relevance of Ekala Dravya Chikitsa.