Periodic Paralysis as a Resonance Disorder - A Universal Resonance Model Interpretation of Ion Channel Instability

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Authors: Anita Domargård
Cited by: 0

Abstract

This paper presents a Universal Resonance Model (URM) interpretation of periodic paralysis as a dynamical instability rather than a structural neuromuscular disorder. Periodic paralysis is analyzed as a resonance failure involving ion channel dynamics, metabolic regulation, and autonomic control. The framework explains episodic weakness, metabolic sensitivity, and reversibility of symptoms through loss of phase coherence and reduced system damping. The work serves as a conceptual validation paper within the URM series and provides a systems-level explanation consistent with known clinical and physiological observations.

Fields of Study & Subjects

Ion channel regulation and function Cardiac electrophysiology and arrhythmias Genetic Neurodegenerative Diseases

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
2 January 2026
Language
EN
Document type
Preprint