Fractal mRNA Processing: A Paradigm Shift in Gene Expression Regulation

Read full text
Authors: Ismail A Mageed
Cited by: 0

Abstract

Traditional models of gene expression regulation often rely on linear or discrete stochastic frameworks to describe the transition from DNA to functional protein. However, emerging evidence suggests that the spatial and temporal organization of messenger RNA (mRNA) processing exhibits fractal properties—self-similar patterns across multiple scales of observation. This paper explores the "Fractal mRNA Processing" hypothesis, arguing that the non-linear, recursive nature of splicing, transport, and decay represents a paradigm shift in our understanding of cellular efficiency. By applying power-law dynamics to transcriptomic data, we demonstrate how fractal organisation allows the cell to manage biological noise and optimise metabolic flux. This framework reconciles the apparent chaos of the nucleoplasm with the high precision of phenotypic outcomes.

Fields of Study & Subjects

RNA and protein synthesis mechanisms RNA Research and Splicing Gene Regulatory Network Analysis

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
3 January 2026
Document type
Preprint