Ferritin–Delirium integrative genomics: analysis code and supplementary materials (v1.0.0)

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Authors: Amirhossein Saed, Mahdi Akbarzadeh, Fatemeh Gohari, Amir Mohammad Jahromizadeh, Nafiseh Asadrouh, Hani Sabaie, Maryam Zarkesh, Mehdi Hedayati, Fereidoun Azizi, MARYAM SADAT DANESHPOUR
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Abstract

Archived analysis code supporting “Serum ferritin and delirium risk: integrative genomic analysis identifies locus-specific signals at 19q13.” The repository provides R scripts implementing two-sample MR, multi-panel SMR/HEIDI screening, and regional variant-sharing analyses using SuSiE–coloc, alongside an interactive supplementary report as HTML within docs/ (also served via GitHub Pages at https://amjahromizadeh.github.io/Ferritin-Delirium/) Inputs and data provenance: This deposit does not redistribute GWAS or QTL summary statistics. Analyses are performed using publicly available summary-statistics resources that must be obtained from their original providers, including serum ferritin GWAS (GWAS Catalog: GCST90270865), delirium GWAS (GWAS Catalog: GCST90473243). LD-dependent steps (SMR, coloc, SuSiE–coloc) use a 1000 Genomes European-ancestry reference panel (PLINK and/or GDS format). Users should download these inputs, ensure compliance with distributor terms, and set local paths as required by the scripts. License. Code is released under the MIT License; Input data remain under the licensing/usage terms specified by their original sources.

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
3 January 2026