Geometric Constraints and Vulnerability in Single-Cell ATAC-seq Immune States: Analysis Pipeline and Data

Reproducible computational pipeline for analyzing immune system geometry and critical transitions using single-cell ATAC-seq data. This package contains: - Information Bottleneck implementation for dimensionality reduction of immune states- Topological Data Analysis (TDA) pipeline for persistence analysis- Vulnerability assessment through minimum viable structure analysis- Processed data tables and metadata for single-cell ATAC-seq immune states- Complete audit log mapping figures to generating scripts for reproducibility Data source: GEO accession GSE194122Analysis methods: Information geometry, topological data analysis, systems immunology