Comparison of the antiglycemic and hypolipidaemic effects of n-hexane and methanol leaf extracts of Nauclea latifolia in alloxan-induced diabetic rats

Diabetes Mellitus has been known to be associated with lipid disorders and cardiovascular complications. The aim of this study was to evaluate and compare the hypoglycemic and hypolipidaemic effects of n-hexane and methanol leaf fractions of Nauclea latifolia in diabetic rats. The induced diabetic rats were administered 150mg/kg and 300mg/kg body weight respectively of the two fractions of Nauclea latifolia or 5mg/kg body weight of glibenclamide for fourteen days. Fasting blood glucose levels were measured and the lipid profile was analyzed. There were significant reductions (p