Evaluation of Fruit Extract of Solanum Lycopersicum for Gastroprotective Effect

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Authors: Nisha Jangde*, Dr. Yashraj Yadav, Dr. Dishant Gupta, Sohan Singh Chouhan, Raksha Goswami
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Abstract

This study investigates the gastro protective potential of the methanolic extract of Solanum lycopersicum fruit waste against aspirin-induced gastric ulcers in mice. The extract was evaluated at doses of 250 mg/kg and 500 mg/kg and compared with a standard drug (Omeprazole, 20 mg/kg). The results demonstrated a significant reduction in ulcer index,with a dose-dependent response. Phytochemical screening revealed the presence of phenolic compounds, flavonoids, tannins, and other secondary metabolites likely responsible for the observed anti-ulcer activity.The findings suggest the potential of Solanumly copersicum fruit extract as a natural therapeutic agent for gastric ulcers.

Fields of Study & Subjects

Helicobacter pylori-related gastroenterology studies Potato Plant Research Bioactive Compounds in Plants

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
4 January 2026