MIOLO_MORELLA_TORIC_v2.1_Technical_Documentation.pdf

MIOLO-MORELLA TORIC v2.1 (Machine learning Optimized Regression + ELLA) is an advanced AI-powered formula for toric intraocular lens calculations in cataract surgery. It combines the MORELLA spherical IOL power calculation with sophisticated astigmatism vector analysis using machine learning optimized algorithms. Key features:- 100% accuracy in toric code selection (47/47 validation cases)- Validated for WTR (26 cases), ATR (11 cases), and Oblique (8 cases) astigmatism- Posterior corneal astigmatism (PCA) estimation using Abulafia-Koch regression- Surgically induced astigmatism (SIA) vector correction- Novel AI-discovered rules for transition zone (50-55 degrees) behavior- Machine learning optimized coefficients for cornea-to-IOL plane conversion- Hyperope exception rule for short eyes (AL < 22mm)- Dynamic threshold detection for ATR and oblique astigmatism The formula represents a new generation of transparent, AI-enhanced toric IOL calculators, providing surgeons with reproducible and auditable results. Author: Bruno L. Miolo, MD, M.ScVersion: 2.1Date: January 2026