The Relationship Between Non-Steroidal Anti-Inflammatory Drug (NSAID) Consumption and the Incidence of Gastritis among Outpatients at the Internal Medicine Clinic of RSUD Prof. Dr. W.Z. Johannes Kupang

Abstract : Background: Gastritis is an inflammatory condition of the gastric mucosa with high prevalence worldwide, especially in developing regions. At RSUD Prof. Dr. W. Z. Johannes Kupang, reported cases increased from 99 in 2021 to 257 in 2023. This research focuses on identifying the association between the type, frequency, and duration of Non-Steroidal Anti-Inflammatory Drug (NSAID) use and gastritis among outpatients. Methods: An analytical observational approach with a cross-sectional design was applied involving 56 patients selected through purposive sampling at the Internal Medicine Clinic. Data were obtained from questionnaire-based interviews and medical record reviews. Bivariate testing was conducted using the contingency coefficient correlation method in SPSS. Results: Thirteen of the 56 participants (23%) were confirmed with gastritis. NSAID use was reported in 84% of respondents, mainly non-selective preparations. Most consumed NSAIDs only when symptoms appeared and for less than five days. Statistical analysis indicated no significant association for frequency (p=0.052) or duration of intake (p=0.052), and a weak significance for NSAID class (p=0.047). Conclusion: NSAID usage patterns showed no meaningful relationship with gastritis incidence among outpatients at RSUD Prof. Dr. W. Z. Johannes Kupang, which may relate to the low intensity and short duration of use.