06 01 Luminal A Base Architecture Invasive Breast Carcinoma NST HR+

Luminal ER+ breast cancer represents 65-70% of all breast cancer cases and exhibits unique biological characteristics: hormonal dependence, metabolic flexibility, and remarkable capacity for late recurrence (10-20 yearspost-diagnosis) [1, 2]. Conventional therapeutic approaches targeting estrogen signaling achieve initial responsesbut face 20-30% recurrence rates due to compensatory mechanisms [3].I try to model this cancer subtype as a adaptive system that could predicted compesatory responses by the carcinoma along with initial mapping of the carcinomas basic Architecture.