07 02 Metastasis Base Architecture Luminal B Invasive Breast Carcinoma NST HER2−

I try to present a mathematical framework for initial modeling Luminal B-like(HER2−) breast cancer metastatic progression across five major anatomical sites: bone (68%incidence), lymph nodes (52%), lung (35%), liver (28%), and brain (12%). The model integrates tissue equilibrium dynamics and site-specific metabolic flux networks among other things.Painting a basic iniitial architecterue of how metastatic evolution evolves manisfests and corelates in Luminal B breast Cancer Metastasis.