08 02 Metastasis Base Architecture Esophageal Squamous Cell Carcinoma ESCC

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

Read full text
Authors: Ionut Alexandru Stefan
DOI: 10.5281/zenodo.18164580
Cited by: 0

Abstract

Esophageal squamous cell carcinoma (ESCC) exhibits distinct metastatic patterns withsite-specific biomechanical adaptations: lymph node (65-75% incidence), lung (25-35%), liver(15-22%), and bone (12-18%). I present a mathematical framework quantifying Corelated evolution, metabolic flux networks, and critical vulnerabilities across these four major metastatic sites.

Fields of Study & Subjects

Mathematical Biology Tumor Growth Cancer Hypoxia and Metabolism Esophageal Cancer Research and Treatment

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
6 January 2026
Language
EN