Identifying membrane-bound transcriptional regulatory proteins from rare but evolutionarily conserved domain combinations

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Authors: Muyoung Lee, Jang, Yeejin, Qingqing Guo, Jonghwan Kim, Edward M. Marcotte
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Abstract

Data for the research paper titled "Identifying membrane-bound transcriptional regulatory proteins from rare but evolutionarily conserved domain combinations." Supplementary Table 2: selected 855 [domain, orthogroup] pairs with their domain, orthogroup annotations, π‘“π‘Žπ‘™π‘™ , 𝑓𝑂𝐺 , conservation-to-frequency values, and corresponding human/mouse proteins. Resource files (parsed information from databases and outputs from softwares) and source codes to 1) calculate conservation-to-frequency values, 2) print out the list of selected [domain, orthogroup] pairs, and 3) draw histograms to check the distribution.

Fields of Study & Subjects

Genomics and Chromatin Dynamics Machine Learning in Bioinformatics Developmental Biology and Gene Regulation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
7 January 2026