CASC3/SGO1 Splicing-Related Dysregulation in Alzheimer's Disease: Cross-Tissue Evidence from Microglia and Cortex

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Francisco Rodríguez‐Esparragón
DOI: 10.5281/zenodo.18177276
Cited by: 0

Abstract

Reproducible R/Bioconductor computational workflow and supplementary data for preprint on SGO1/CASC3 dysregulation in Alzheimer's disease. Datasets analyzed: - GSE153873: Bulk RNA-seq post-mortem AD microglia (n=12 AD vs n=10 controls) - GSE109887: Illumina 450k MTG methylome (AD vs Control) Generates: - Table1: 1,247 DEGs microglia FDR

Fields of Study & Subjects

Neuroinflammation and Neurodegeneration Mechanisms Alzheimer's disease research and treatments Cerebrovascular and genetic disorders

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
8 January 2026
Document type
Preprint