Clinical outcomes following infection of 8-week-old piglets with the porcine reproductive and respiratory syndrome virus 1 (PRRSV-1) Lleida 029_22 strain.

(A) Daily rectal temperatures of pigs after infection. The red dotted line indicates the threshold for high fever (>41°C). Data are presented as mean ± SD. (B) Daily average clinical scores after PRRSV infection. Data are shown as mean ± SEM. Different letters indicate significant statistical differences (p < 0.05) between groups: intramuscular (IM) vs intranasal (IN) (a), IM vs Control (C) (b) and IN vs C (c). (C) Mortality and survival curves for each experimental group.