Dementia Is Not Memory Loss, but a Breakdown of Temporal Order — A Phase-Based Interpretive Framework for Disease Progression

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Authors: Dae-gon Yun
Cited by: 0

Abstract

Dementia is commonly described as a disease of memory loss.However, this definition fails to account for several core clinical features, including non-linear deterioration, intermittent clarity, stress sensitivity, partial recovery after sleep, and late-stage acceleration. This paper proposes an alternative interpretive coordinate system:dementia is not a failure to generate cognitive function, but a breakdown of temporal order.More precisely, it is defined as a condition in which phase alignment in collective neural dynamics can still be generated, but the cost of maintaining that alignment becomes structurally unsustainable. Within this framework, phenomena often treated as “individual differences” or “variability” are reinterpreted as reflections of proximity to a critical threshold of temporal instability. Disease progression is thus examined not through average decline, but through variability, event-like transitions, and the sustainability of relational structure over time. To clarify the structural scope of this perspective, Parkinson’s disease and cancer are included as contrast cases. Parkinson’s disease is interpreted as a condition of excessive alignment and local phase fixation, while cancer is positioned as an extreme case of global phase fixation characterized by failure of termination. These comparisons are not intended to unify diseases by cause or mechanism, but to demonstrate distinct modes by which temporal order can fail. Importantly, this paper does not propose treatments, molecular mechanisms, or intervention protocols.Its sole aim is to redefine what questions should be asked in disease research, and which questions may be structurally insufficient when temporal progression itself is at issue. Rather than offering answers, this work provides a coordinate system that makes it difficult to continue asking disease progression in the same way as before.

Fields of Study & Subjects

Sleep and Wakefulness Research Functional Brain Connectivity Studies Neural dynamics and brain function

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
9 January 2026
Document type
Preprint