ASSESSMENT OF IMMUNOLOGICAL REACTIVITY IN BLEEDING COMPLICATIONS OF GASTRIC AND DUOVENAL ULCERS AND ITS CLINICAL SIGNIFICANCE

Gastric and duodenal ulcers, when complicated by bleeding, are still an urgent problem of emergency gastroenterology and surgery. In such cases, along with morphological changes, impaired immunological reactivity also plays an important role in the development of the disease. In experimentally formed gastric ulcers, an almost twofold decrease in the total number of thymocytes was observed, which is mainly explained by the effect of stress. Under the influence of stress factors, the number of cells in the lymph nodes, bone marrow (bone marrow) and thymus decreases significantly. Also, negative changes are observed in the processes of rosette formation and anti-tellogenesis.