THE TUMOR IMMUNE MICROENVIRONMENT AS A KEY DETERMINANT OF DISEASE PROGRESSION AND THERAPEUTIC RESPONSE IN HPV-ASSOCIATED CERVICAL CANCER
Abstract
This thesis synthesizes current concepts of HPV-driven immune remodeling across disease stages, highlights TIME features associated with progression and outcome, and discusses actionable translational strategies—including biomarker-guided immunotherapy combinations, microenvironment reprogramming, and multi-omics profiling—to improve responses and durability of control.
Fields of Study & Subjects
Cervical Cancer and HPV Research
Cancer Immunotherapy and Biomarkers
Endometrial and Cervical Cancer Treatments
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 9 January 2026