Computational Identification of Purine Nucleoside Phosphorylase and Estrogen Receptor 1 as Biomarkers of Acetaminophen-induced Liver Injury
Abstract
We computationally analyze network toxicology and transcriptomic data to identify biomarkers of acetaminophen-induced liver injury, revealing estrogen receptor 1 and purine nucleoside phosphorylase as diagnostic targets.
Fields of Study & Subjects
Drug-Induced Hepatotoxicity and Protection
Computational Drug Discovery Methods
Bioinformatics and Genomic Networks
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 9 January 2026
- Document type
- Dataset