Computational Identification of Purine Nucleoside Phosphorylase and Estrogen Receptor 1 as Biomarkers of Acetaminophen-induced Liver Injury

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Authors: Li Huhu
Cited by: 0

Abstract

We computationally analyze network toxicology and transcriptomic data to identify biomarkers of acetaminophen-induced liver injury, revealing estrogen receptor 1 and purine nucleoside phosphorylase as diagnostic targets.

Fields of Study & Subjects

Drug-Induced Hepatotoxicity and Protection Computational Drug Discovery Methods Bioinformatics and Genomic Networks

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
9 January 2026
Document type
Dataset