How do gender differences affect the pharmacokinetics and pharmacodynamics of medications?

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Tripdatabase
DOI: 10.5281/zenodo.18202841
Cited by: 0

Abstract

Gender differences significantly affect both pharmacokinetics and pharmacodynamics of medications, influencing drug dose requirements, efficacy, and safety profiles. Notable differences are observed in various therapeutic areas, though further research is needed to clarify underlying mechanisms and optimize gender-specific pharmacotherapy.

Fields of Study & Subjects

Pharmacogenetics and Drug Metabolism Sex and Gender in Healthcare Estrogen and related hormone effects

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
2 January 2026