What is the mechanism of action of Lecanemab at the neuronal and cellular level in treating Alzheimer's disease?
Abstract
Lecanemab acts by binding to soluble amyloid-beta protofibrils, reducing amyloid plaques and neurotoxicity, potentially slowing Alzheimer's progression in early disease stages.
Fields of Study & Subjects
Alzheimer's disease research and treatments
Dementia and Cognitive Impairment Research
Neuroinflammation and Neurodegeneration Mechanisms
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 9 January 2026