Psoriatic Disease as a Systems Transition — A Universal Resonance Model (URM) Perspective

Psoriatic disease, encompassing psoriasis and psoriatic arthritis, is a heterogeneous immune-mediated condition with highly variable expression in skin and joints. This paper presents a conceptual interpretation of psoriatic disease as a long-term systems transition from a Universal Resonance Model (URM) perspective. Disease dynamics are described in terms of declining resilience, maladaptive resonance between immune, skin, joint, and metabolic loops, multi-attractor behavior with possible switching between skin-dominant, joint-dominant, and mixed states, and eventual attractor lock-in. Biomarkers and clinical measures are interpreted as phase and attractor indicators rather than static disease labels, and therapeutic effects are viewed as inherently phase- and attractor-dependent and critically timing-sensitive. Conceptual framework only; no new experimental, clinical, or epidemiological data are included.