DIAGNOSIS AND TREATMENT OF REPRODUCTIVE DISORDERS IN HYPOTHYROIDISM

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Authors: Dilafruz Kazakova, Komila Xayitboyeva
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Abstract

Hypothyroidism is a common endocrine disorder that predominantly affects women of reproductive age and is closely associated with menstrual disturbances, ovulatory dysfunction, infertility, and adverse reproductive outcomes. Thyroid hormone deficiency disrupts the hypothalamic–pituitary–ovarian axis and is frequently accompanied by secondary hyperprolactinemia, further impairing reproductive function. This study was conducted at the Khorezm branch of the Republican specialized scientific and practical medical center of endocrinology and aimed to comprehensively evaluate diagnostic approaches and treatment strategies for reproductive disorders in women with hypothyroidism. Patients were stratified into study groups based on thyroid status and reproductive function. The findings confirm that early diagnosis and optimized levothyroxine therapy significantly improve reproductive outcomes.

Fields of Study & Subjects

Thyroid Disorders and Treatments Ovarian function and disorders Reproductive Health and Technologies

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
11 January 2026