Processed bulk and snRNA-seq data: Multicellular signaling and partial recovery define reverse cardiac remodeling

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Authors: Marco Steier, Inés Rivero-García, Ricardo O. Ramirez Flores, Anushka Deshpande, Julian Poetzsch, Sumra Nazir, Irsiya Aijaz, Marina Talamini, Volker Ast, Katharina Mößinger, Matthias Dewenter, Benjamin Meder
+5 more Manju Kumari, Backs, Johannes, Ashraf Yusuf Rangrez, Julio Sáez-Rodríguez, Norbert Frey
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Abstract

This deposition contains processed transcriptomics data of adult mouse left ventricle tissue and corresponding to the manuscript Multicellular signaling and partial recovery define reverse cardiac remodeling (https://doi.org/10.64898/2026.01.12.699040). Included files: Bulk RNA-seq raw count matrix. Metdata corresponding to the bulk RNA-seq raw counts. Annotated AnnData object. Data analysis Scripts used for data analysis can be found at https://github.com/saezlab/heart_revremod_paper.

Fields of Study & Subjects

Cardiac Fibrosis and Remodeling Single-cell and spatial transcriptomics Congenital heart defects research

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
11 January 2026
Document type
Dataset