What are the hepatic considerations or potential liver-related side effects when prescribing solifenacin?
Abstract
Solifenacin has specific hepatic considerations due to increased plasma levels in impaired liver function, especially contraindicated in severe impairment and limited to 5 mg in moderate impairment.
Fields of Study & Subjects
Pharmacogenetics and Drug Metabolism
Drug-Induced Hepatotoxicity and Protection
Urinary Bladder and Prostate Research
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 11 January 2026