Lipidomics and metabolomics dataset for: Methionine metabolism is linked with phospholipid and glutamine metabolism to drive ferroptosis

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Authors: JongWoo Kim, Seo Young Jang, Yeon Jin Roh, Yeajin Ju, Choi, Dong Wook, Geum-Sook Hwang, Eun-Woo Lee
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Abstract

This deposit provides lipidomics and metabolomics data generated from lung cancer cells under cystine/cysteine deprivation with methionine perturbation (±methionine depletion and ±SAM rescue, where applicable). The deposit includes raw instrument files (when available), aligned/quantified feature tables, identification/annotation outputs, and sample metadata. The accompanying README summarizes experimental groups, replicates, normalization/processing steps, and how each file maps to figures/tables in the manuscript titled 'Methionine metabolism is linked with phospholipid and glutamine metabolism to drive ferroptosis'.

Fields of Study & Subjects

Ferroptosis and cancer prognosis Cancer Lipids and Metabolism Sulfur Compounds in Biology

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
12 January 2026
Document type
Dataset