"Pressure, Perfusion, and Prostheses": Microcirculatory Changes Beneath Maxillary Dentures"-A Review.
Abstract
The palatal mucosa is very important for supporting maxillary dentures, and its health depends a lot on a healthy microcirculatory system. Putting in an upper (maxillary) denture puts constant mechanical stress and pressure on the palatal tissues, which can have a big effect on local blood flow. This review looks at how upper dentures affect the microcirculation of the palate, focusing on how vascular compression, ischemia, and adaptive tissue responses work. Experimental and clinical studies employing methodologies such as xenon clearance and laser Doppler flowmetry indicate a decrease in palatal blood flow immediately following denture insertion, with more significant alterations observed during extended or continuous usage. Chronic impairment of microcirculation can result in epithelial hyperplasia, connective tissue fibrosis, inflammation, and heightened vulnerability to denture-associated mucosal lesions, such as denture stomatitis. Factors related to the prosthesis, such as how well the denture fits, how much of the palate it covers, the properties of the material, and the design of the relief, as well as factors related to the patient, such as their age and systemic vascular status, all affect how bad the changes in microcirculation are. To make the best dentures, improve tissue tolerance, and stop long-term palatal mucosal pathology, you need to know about these changes in the blood vessels. Key Words: Maxillary complete denture; Palatal microcirculation; Mucosal blood flow; Denture-induced ischemia; Denture stomatitis.
Fields of Study & Subjects
Dental materials and restorations
Oral Health Pathology and Treatment
Oral microbiology and periodontitis research
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 12 January 2026