FLASH-MM: fast and scalable single-cell differential expression analysis using linear mixed-effects models

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Changjiang Xu, Delaram Pouyabahar, Véronique Voisin, Hamed Heydari, Gary D. Bader
DOI: 10.5281/zenodo.18222186
Cited by: 0

Abstract

FLASH-MM is a method for analysis of single-cell differential expression using a linear mixed-effects model (LMM). The mixed-effects model is a powerful tool in single-cell studies due to their ability to model intra-subject correlation and inter-subject variability.

Fields of Study & Subjects

Single-cell and spatial transcriptomics Gene expression and cancer classification Gene Regulatory Network Analysis

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
12 January 2026