Bi-directional cellular crosstalk drives inflammation in synovial niches of rheumatoid arthritis patients

This repository contains code and data for the analysis of data from the manuscript: Bi-directional cellular crosstalk drives inflammation in synovial niches of rheumatoid arthritis patients Mirjam Dellinger1,2, Juan Manuel Sacnun1, Lisabeth Emilius1, Maximilian Kugler1, Felix Kartnig1, Elisabeth Simader1, Marie Brinkmann1, Bianca Luckerbauer1, Teresa Preglej1, Melanie Acosta1, Elena Pontarini3, Liliane Fossati-Jimack3, Stefan Kubicek4, Giulio Superti-Furga4,5, Renate Kain6, Leonhard Heinz1, Günter Steiner1,2, Daniel Aletaha1, Felice Rivellese3, Costantino Pitzalis3,7, Anela Tosevska1#, Michael Bonelli1,2#* and Thomas Karonitsch1# 1Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Austria 2Ludwig Boltzmann Institute for Arthritis und Rehabilitation, Vienna, Austria 3Centre for Experimental Medicine and Rheumatology, William Harvey Research Institute, Queen Mary University and The London School of Medicine and Dentistry, London, UK 4CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria 5Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria 6Department of Pathology, Medical University of Vienna, Austria 7Department of Biomedical Sciences, Humanitas University & IRCCS Humanitas Research Hospital, Milan, Italy #contributed equally