DeepBurst: Predicting transcriptional burst kinetics from histone modifications with deep learning

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Authors: Han Wang, Zhenquan Zhang, Zhiwei Huang, Xiaochen Yu, Zihao Wang, Hongyu Qiu, Jiajun Zhang
Cited by: 0

Abstract

This record releases the processed datasets and pretrained DeepBurst model weights (checkpoints) for reproducing our experimental results and for downstream applications. DeepBurst is a deep-learning framework that leverages histone-modification features to predict transcriptional bursting–related phenotypes (e.g., classification/decision tasks for burst frequency and burst size, as defined in the manuscript).

Fields of Study & Subjects

Genomics and Chromatin Dynamics Gene Regulatory Network Analysis Single-cell and spatial transcriptomics

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
13 January 2026
Language
EN