Next-Generation Epidermal Patches: Bridging 3D and Multidimensional Printing for Biomedical and Cosmetic Innovation

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Authors: Labiba Khalil El-Khordagui, Salma E. El-Habashy, Abdolreza Simchi, Hebat‐Allah S. Tohamy, Maria Letizia Focarete, Mariangela Rea, Luana Di Lisa, Snigdha Roy Barman, Amit Nain, Ovidio Catanzano, Joshua Ofori Boateng, Jagan Mohan Dodda
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Abstract

The Dataset provides a comprehensive overview of 3D-printed epidermal patches, encompassing both conventional (non-microneedle) and microneedle-integrated platforms. Particular emphasis is given to innovative materials such as self-oxygenating hydrogels and nanomaterial-free bioinks based on proteins and polysaccharides, alongside nanocomposite variants. We discuss 3D printing techniques for acellular constructs, cell-laden matrices, and microneedle array patches (MAPs), as well as emerging multidimensional 4D and 5D strategies. We discuss integrated printed patches with wearable sensors, smart devices, and artificial intelligence (AI), which represents a transformative frontier in personalized cosmetics, enhancing product efficacy and consumer satisfaction in both ingredient use and formulation design.

Fields of Study & Subjects

3D Printing in Biomedical Research Hydrogels: synthesis properties applications Advancements in Transdermal Drug Delivery

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
13 January 2026
Document type
Dataset