What are the general principles for dose adjustment of doxorubicin in patients receiving RCHOP who are also on antidepressants?

Zenodo (CERN European Organization for Nuclear Research) 2026 Open access

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Authors: Tripdatabase
DOI: 10.5281/zenodo.18237141
Cited by: 0

Abstract

The evidence suggests a theoretical interaction between doxorubicin and antidepressants via CYP450 enzymes, but specific dose adjustment guidelines for patients on RCHOP are not well-documented.

Fields of Study & Subjects

Pharmacogenetics and Drug Metabolism Chemotherapy-induced cardiotoxicity and mitigation Safe Handling of Antineoplastic Drugs

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
13 January 2026