Do antidepressants like fluoxetine affect the efficacy or toxicity of doxorubicin when used in RCHOP chemotherapy?
Abstract
The clinical implications of combining fluoxetine with doxorubicin in RCHOP chemotherapy are not well-defined due to a lack of direct studies; theoretical interactions based on metabolic pathways could exist.
Fields of Study & Subjects
Chemotherapy-induced cardiotoxicity and mitigation
Pharmacogenetics and Drug Metabolism
Pharmacovigilance and Adverse Drug Reactions
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 13 January 2026