CENTRAL HEMODYNAMICS IN SANGUINES AND MELANCHOLICS

Scientific physiological publications contain a sufficiently deep analysis of quantitative and qualitative changes in hematological indicators caused by the formation of stress reactions to stress factors of various genesis. The formation of stress reactions and adaptive reactions is controlled by the central nervous system, namely the autonomic nervous system and had a certain dependence on the type of higher nervous activity. Based on the above, it can be assumed that the type of higher nervous activity (HNA) affects not only blood indicators, but also other functional indicators of the body, including indicators of central hemodynamics. The purpose of our study is to conduct a comparative analysis of indicators of central hemodynamics and integrative hemodynamic indices in sanguine and melancholic individuals. The work was carried out in accordance with bioethical norms in compliance with the relevant principles of the Helsinki Declaration of Human Rights, the Council of Europe Convention on Human Rights and Biomedicine and the relevant laws of Ukraine. When comparing the indicators of central hemodynamics, it should be noted that the maximum values were characteristic of sanguine people (pulse 98.8 beats/min, blood pressure 139/76 mmHg, minute blood volume 6.9 l/min, left ventricular output 1.7 W); the minimum adaptive reserves were characteristic of melancholics (vegetative Kerdo index -3.9 с.u.), the maximum adaptive reserves were characteristic of sanguine people (vegetative Kerdo index -7.44 с.u.); the maximum energy expenditure to ensure blood circulation was characteristic of sanguine people (6340.3 с.u.) compared to melancholics (4704.57 с.u.). Thus, the indicators of central hemodynamics indicated the formation of signs of functional load in the activity of the heart in sanguine people with a slight tendency to compensate the vascular bed to facilitate the work of the heart; minimal adaptive capabilities and reserves were characteristic of melancholics.