COMPARATIVE EFFICACY AND SAFETY OF INTRAMUSCULAR MIDAZOLAM VERSUS INTRAVENOUS LORAZEPAM IN PREHOSPITAL MANAGEMENT OF STATUS EPILEPTICUS: EVIDENCE FROM RAMPART TRIAL
Abstract
Background: Status Epilepticus (SE) is a life-threatening neurological emergency that requires immediate treatment. Intravenous (IV) lorazepam is a standard first-line therapy, but IV access is often delayed in Prehospital settings. Intramuscular (IM) Midazolam offers a potential alternative due to its ease of administration. Objective: To evaluate and compare the effectiveness of IM midazolam and IV lorazepam in terminating seizures in patients with status epilepticus in a Prehospital setting.
Fields of Study & Subjects
Epilepsy research and treatment
Anesthesia and Sedative Agents
Electroconvulsive Therapy Studies
Publication details
- Journal / source
- World Journal of Pharmaceutical Research
- Publication date
- 16 January 2026
- Language
- EN