What are the comparative benefits and harms of early HRT formulations versus current formulations?
Abstract
While both early and current HRT formulations effectively manage menopausal symptoms, newer formulations, especially transdermal options, may offer reduced risk for cardiovascular disease and breast cancer compared to older oral formulations, provided treatment initiation is appropriately timed.
Fields of Study & Subjects
Menopause: Health Impacts and Treatments
Estrogen and related hormone effects
Hormonal and reproductive studies
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 14 January 2026