CellRefiner v1.0.0

CellRefiner is a physical model-based method that integrates a scRNA-seq dataset with a paired spatial transcriptomics (ST) dataset to generate single-cell resolution in the imputed ST data. CellRefiner models cells as particles connected by forces, and then optimizes cell locations with spatial proximity constraints, gene expression similarity, and ligand-receptor interactions between cells.This is the release accompanying the publication.