Example of the simulation algorithm for the article "Intrinsic limits of timekeeping precision in gene regulatory cascades"
Abstract
This repository has the following files: manuscript.pdf: A copy of the manuscript explaining the theoretical basis of the timing process using a gene expression cascade. CascadeSimulation.ipynb (jupyter notebook): Example of the simulation code (python language) used to estimate the gene expression dynamics of two-gene cascade and the optimization of activation threshold that minimizes the first passage time noise.
Fields of Study & Subjects
Gene Regulatory Network Analysis
stochastic dynamics and bifurcation
Circadian rhythm and melatonin
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 16 January 2026
- Document type
- Book