Imaging Mass Cytometry dataset of lymph node tissue of patients undergoing curative-intent resection for non-small cell lung cancer

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Authors: Zhan Hao Xi, Yusuke Koga, Sarah A. Mazzilli, Joshua David Campbell, Kei Suzuki
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Abstract

Lymph node tissue samples were obtained from surgical specimens of patients undergoing curative-intent resection at Boston Medical Center. Samples were selected for imaging mass cytometry (IMC) to profile and compare spatial features across patients with different tumor stages and across lymph node locations. FFPE tissue sections were stained with a panel of 40 metal-conjugated antibodies and imaged using the Hyperion Imaging System at a spatial resolution of 1 μm and an ablation frequency of 200 Hz.

Fields of Study & Subjects

Cancer Immunotherapy and Biomarkers Single-cell and spatial transcriptomics Mass Spectrometry Techniques and Applications

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
18 January 2026
Language
EN
Document type
Dataset