Can a patient use sertraline and promethazine together, and would zopiclone be a better replacement for promethazine?

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Authors: Tripdatabase
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Abstract

The evidence suggests that while zopiclone may have a favorable interaction profile, there is no direct evidence favoring it over promethazine in patients using sertraline.

Fields of Study & Subjects

Pharmacogenetics and Drug Metabolism Treatment of Major Depression Pharmaceutical Practices and Patient Outcomes

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
16 January 2026