Evaluation of Hydro-Alcoholic Root Extract of Nyctyanthes Arbortristis for Antidiabetic Activity on Wistar Albino Rats

Ayurveda is the traditional system of treatment using the plants for treating various alignment. Nyctanthus arbortristis Linn. (Oleaceae) popularly known as ‘Night Jasmin’ is one of the magical plants having great medicinal value. The root of Nyctanthes arbortristis Linn. possess several phytoconstituents like, alkaloids, flavonoids, phenols, steroids, coumarins, resins and carbohydrates. The antidiabetic activity of hydro-alcoholic root extract of N. arbortristis has not been scientifically investigated so far. The aim is to investigate the antidiabetic activity of hydro-alcoholic root extract of Nyctanthes arbortrisis. In this study, rats with diabetes brought on by alloxan monohydrate were treated with the hydro-alcoholic root extract of Nyctanthus arbortristis (HARNA). The diabetic rats were gavaged with glibenclamide (10 mg/kg) and HARNA (200, 250 and 300 mg/kg) at different doses for fifteen days in a row. The HARNA showed more significant (p