Epigenetic silencing in ulcerative colitis.

Zenodo (CERN European Organization for Nuclear Research) 2026 Preprint Open access

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Authors: Shahan Mamoor
DOI: 10.5281/zenodo.18267825
Cited by: 0

Abstract

We present evidence here for widespread epigenetic silencing in ulcerative colitis. Dnmt1, Ep300 and Ep400 were all among the genes most significantly silenced transcriptome-wide in ulcerative colitis compared to healthy controls, in the blood. The data describe an epigenetic silencing event governed by a maintenance DNA methyltransferase in inflammatory bowel disease.

Fields of Study & Subjects

Epigenetics and DNA Methylation Inflammatory Bowel Disease Genomics and Chromatin Dynamics

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
16 January 2026
Document type
Preprint