An Overview on Antidiabetic Disease

Diabetes Mellitus (DM) is a rapidly escalating global health crisis affecting hundreds of millions, requiring complex, self-managed care that is highly susceptible in response. This project provides a comprehensive overview of the current landscape of antidiabetes disease management, focusing specifically on the critical interplay between therapeutic efficacy and the inevitability of human-centric failures. While significant research effort is directed toward novel pharmacotherapies (e.g., GLP-1 agonists, SGLT2 inhibitors), the realized effectiveness of these treatments is often dramatically reduced by errors in prescription, patient adherence, self-monitoring, and device use (e.g., insulin pens and pumps). This review synthesizes current knowledge on the most frequent and impactful categories of human error including slips, lapses, and mistakes within the context of DM care. Ultimately, this project establishes a critical need for a paradigm shift in diabetes research, arguing that future antidiabetes strategies must move beyond solely targeting biological pathways to incorporate human-factors engineering and error-reduction design to create more robust, safer, and inherently user-friendly management systems.