Design Formulation and Evaluation of Nanoparticles
Abstract
One of the most revolutionary developments in contemporary science, nanotechnology holds enormous promise for the health, industrial, and environmental sectors. This paper provides a comprehensive overview of the design, formulation, assessment, classification, production methods, and applications of nanoparticles. Due to their surface features and nanoscale size, nanoparticles ranging from organic to composite and carbon-based systems exhibit distinct physicochemical properties. The concepts of nanoparticle engineering prioritize accurate control over surface functionalization, charge, size, and shape in order to maximize targeting efficiency, stability, and biocompatibility. Numerous synthesis methodologies, such as top-down, bottom-up, and green biological approaches, are examined with an emphasis on their benefits, drawbacks, and applicability for various materials. The evaluation of homogeneity, stability, and drug release kinetics requires the use of sophisticated characterization techniques such as DLS, zeta potential, and microscopy. Although toxicity, large-scale production, and regulatory uniformity continue to be obstacles, applications include medicine delivery, diagnostics, catalysis, and energy systems. As to the review's findings, the future generation of nanoparticle-based technologies will be defined by the integration of sustainable and intelligent responsive nanocarriers.
Fields of Study & Subjects
Nanoparticle-Based Drug Delivery
Nanoparticles: synthesis and applications
Chemical and Physical Properties of Materials
Publication details
- Journal / source
- Zenodo (CERN European Organization for Nuclear Research)
- Publication date
- 16 January 2026