What are the most effective pharmacological treatments for managing fibromyalgia symptoms in adults?

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Authors: Tripdatabase
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Abstract

FDA-approved treatments such as pregabalin and duloxetine demonstrate strong efficacy for fibromyalgia management, while alternative therapies like amitriptyline and low-dose naltrexone offer potential benefits but require further validation.

Fields of Study & Subjects

Fibromyalgia and Chronic Fatigue Syndrome Research Pain Mechanisms and Treatments Musculoskeletal pain and rehabilitation

Publication details

Journal / source
Zenodo (CERN European Organization for Nuclear Research)
Publication date
16 January 2026